Angelantoni Life Science’s series of biological safety cabinets represents the high quality range of microbiological cabinets that protects the operator, the product and the environment. This line is synonymous with technological excellence and translates into safety, reliability and
comfort.
STERIL represents a wide range of laminar and horizontal flow cabinets for microbiology, biology, chemistry and electronics laboratories, for the preparation of antiblastic drugs or genetic sequencing and engineering.
The biological or microbiological safety cabinets, also called biohazard cabinets, are primary collective protective equipment present in every biological laboratory as they protect the operator and the work environment from the risk of exposure to aerosols of potential pathogens
Some versions of the range are also used to ensure operator safety and sterile conditions of the handled product, as in the case of cell culture or in the preparation of chemotherapy drugs.
The biohazard hoods are divided into two types based on laminar flow direction:
• Horizontal laminar flow hood (HELIOS)
• Vertical laminar flow hood (GEMINI, POLARIS)
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CLASS I
CLASS I:
HHoods with front opening, protection is achieved thanks to the air flow direct from the outside to the inside of the hood through the front opening. Environmental protection is achieved through a HEPA filter in the exhaust system. They do not protect the sample from contamination and are suitable for use with biological agents with low and medium handling risk
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CLASS II
CLASS II
Hoods designed to protect both the operator and the sample. These hoods consist of a perforated stainless steel top, which allows the air previously filtered to enter through a HEPA filters system, one at the inlet and one at the outlet. 30 % of the air comes out of these hoods, while the remaining 70 % remains inside them, ensuring complete sterile conditions. The air enters the hood with a vertical flow, so that microorganisms are unable to leave the work environment and do not contaminate the operator. (BIOBAN, STERILSAFE, STERILSAFE EVO, STERILSAFE TE, VBH, CTH, CTH EVO, TOPFLOW)
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CLASS III
CLASS III:
Fully hermetically sealed hoods, operate at negative pressure and manipulations inside the hood are carried out using gloves inserted into the hood structure, hence the name “glove box”. They are equipped with a HEPA filter on the inlet air and a double HEPA filter on the outlet air, allowing total protection of the operator and the environment. They are therefore suitable for handling high biological risk and are also used when handling carcinogens and antiblastic agents. (CYTOBOX, CYTOBOX LIGHT);
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CLASS ISO III
CLASS ISO 3:
According to EN standard 14644-1: These cabinets are used in all situations where the product needs to be protected from harmful effects due to the uncontrolled spread of airborne contaminants during handling. (GEMINI, POLARIS, HELIOS)
CLASS II MICROBIOLOGICAL SAFETY HOODS
Class II hoods provide protection to both the operator and the sample, assuring complete sterile conditions. They consist of a perforated stainless steel top, which allows the air previously filtered to enter through a 2 HEPA filters system, placed at close range. 30 % of the air escapes to the outside, while the remaining 70 % remains in the hood. The air enters the hood with a vertical flow, so that microorganisms are unable to leave the work environment and do not contaminate the operator (in case of pathogenic microorganisms). Indicated for handling group II and group III microorganisms.
Sterilsafe
CLASS II A
Certified by TÜV Rheinland Group according to EN 12469:2000
Sterilsafe Data sheet
Sterilsafe 48 - 72 Data sheet
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The STERILSAFE line is used in all situations where it is required to protect the operator and the environment from the harmful effects of uncontrolled spreading of airborne contaminants and, equally, to ensure that no environmental interference of a microbiological nature can affect the product during its handling.
The STERILSAFE model is made of powder-coated stainless steel, with a worktop that can be adjusted into segments and is lit. The walls are made of tempered glass and front screen with electronic opening.
The ventilation system is built using two centrifugal fans that feed a unidirectional air flow towards the work area, while the recirculation and exhaust air filtration is carried out with HEPA H14 filters with 99.995% MPPS efficiency.
Basis configuration:
- Perforated top, divided into sectors
- Power socket (2 sockets in models 60 and 72)
- DEHS port 100 %
- Vacuum tap
- Gas tap with solenoid valve
Optional accessories:- Blind top, divided in sectors (on request, with no surcharge)
- Floor support
- UV lamp
- Additional power sockets
- Armrests (pair)
- Chest of drawers on wheels
- Gas/nitrogen/vacuum/compressed air taps
- Additional power socket
- Dry contact NA/NC
- Blind side walls (on request, with no surcharge)
- Touch screen controller
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The STERILSAFE EVO line is used in all situations where it is required to protect the operator and the environment from the harmful effects of uncontrolled spreading of airborne contaminants and, equally, to ensure that no environmental interference of a microbiological nature can affect the product during its handling.
The STERILSAFE EVO model is made of powder-coated stainless steel, with a worktop that can be adjusted into segments and is lit. The walls are made of tempered glass and front screen with electronic opening.
The ventilation system is built using two low-consumption DC fans that feed a unidirectional air flow towards the work area, while the recirculation and exhaust air filtration is carried out with HEPA H14 filters with 99.995 % MPPS efficiency.
Basis configuration:
- Perforated top, divided into sectors
- Power socket (2 sockets in models 60 and 72)
- DEHS port 100 %
- Vacuum tap
- Gas tap with solenoid valve
Optional accessories:- Blind top, divided in sectors (on request, with no surcharge)
- Floor support
- UV lamp
- Additional power sockets
- Armrests (pair)
- Chest of drawers on wheels
- Gas/nitrogen/vacuum/compressed air taps
- Additional power socket
- Dry contact NO/NC
- Blind side walls (on request, with no surcharge)
- Touch screen controller
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The line VBH is used in Microbiology, Virology, Haematology and Oncology
laboratories.
It grants the option to work cell cultures, recombinant DNA, viruses and pathogens. The VBH model is made of powder-coated stainless steel, with a worktop that can be adjusted into segments and is lit. The tilting front screen is equipped with gas springs made of shatterproof laminated glass.
The ventilation system is created using 2 centrifugal fans, one of which is dedicated to the unidirectional air flow towards the work area, accounting for 70% of the air involved; the other dedicated to the amount of ejected air, equal to 30%. In the event of a fan malfunction, the other is able to ensure the protection efficiency of the front barrier during the emergency stage.
Basis configuration:
- Perforated worktop
- Power socket
- Vacuum circuit with tap
- Gas tap with solenoid valve
- Front closure panel in anodised aluminium
- Blind top, divided in sectors (on request, with no surcharge)
- Floor support
- UV lamp (mounted on the front closure panel)
- Armrests (pair)
- Chest of drawers on wheels
- Additional activated carbon exhaust filter (without collar)
- Additional power socket
- Compressed air circuit with tap
- Nitrogen circuit with manual tap
- Dry contact NA/NC
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The BIOBAN model is made of powder-coated stainless steel, with a worktop that can be adjusted into segments and is lit. The walls are made of tempered glass and front screen with electronic opening.
The ventilation system consists of:
• one fan in BIOBAN versions
• two fans in BIOBAN DF versions
which feed a unidirectional air flow towards the work area, while the recirculation and exhaust air filtration is carried out with HEPA H14 filters with 99.995 % MPPS efficiency
Basis configuration:
- Perforated top, divided into sectors
- Power socket (1 socket for 36 and 48, 2 sockets for 60 e 72 models)
- DEHS port 100 %
- Side window
- Through holes on the side windows for any tap installations or connections with scales
Optional accessories:
- Blind top, divided in sectors (on request, with no surcharge)
- Floor support
- UV lamp
- Additional power sockets
- Armrests (pair)
- Chest of drawers on wheels
- Gas/nitrogen/vacuum/compressed air taps
- Additional power socket
- Dry contact NA/NC
- Blind side walls (on request, with no surcharge)
Sterilsafe TE (Total Exhaust)
CLASS II A Typ B2
100 % Exhaust air according to NSF / ANSI 49
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STERILSAFE TE (Total Exhaust) class II hoods with total exhaust air involved (B2) belong to the latest generation of laminar air flow systems where construction with the highest quality materials ensures compliance with the strictest safety standards.
STERILSAFE TE are microbiological safety cabinets with 100% of air ejected according to NSF / ANSI 49; they are designed to provide protection to the operator, the product (ISO 5 according to ISO/EN 14644-1) and the environment and to eject 100 % of the air outside the building.
Commonly used in laboratories to handle volatile toxic chemicals and radionuclides. They are also required in a wide range of applications such as: microbiology, virology, haematology, cell culture, genetics, handling of agents hazardous to humans or animals.
The STERILSAFE TE model is made of powder-coated stainless steel, with a worktop that can be adjusted into segments and is lit.
Equipped with a special inclined top to facilitate air filter maintenance and replacement. The walls are made of tempered glass and front screen with electronic opening. The ventilation system is built using two centrifugal fans that feed a unidirectional air flow towards the work area, while the recirculation and exhaust air filtration is carried out with HEPA H14 filters with 99.995 % MPPS efficiency
Basis configuration:
- Perforated top, divided into sectors
- Power socket (2 sockets in models 60 and 72)
- DEHS port 100 %
- Vacuum tap
- Gas tap with solenoid valve
Optional accessories:
- Blind top, divided in sectors (on request, with no surcharge)
- Floor support
- UV lamp
- Additional power sockets
- Armrests (pair)
- Chest of drawers on wheels
- Gas/nitrogen/vacuum/compressed air taps
- Additional power socket
- Dry contact NA/NC
- Blind side walls (on request, with no surcharge)
- Touch screen controller
MICROBIOLOGICAL SAFETY HOODS FOR CYTOTOXIC DRUGS
Safety cabinet suitable for the preparation of cytotoxic and chemotherapeutic drugs, and for the manipulation of biological agents, in hospital pharmacies, oncology wards, day hospitals and pharmaceutical industries.
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The CTH model is designed to meet three protection levels:
1. Protection of the operator: The containment index, evaluated over the total surface area of the frontal suction area, is equal to or less than 5 CFU for a non-turbulence test or APF equal to or greater than 1x105 according to EN12469;
2. Protection of the product: Cleanliness of the air in the working area in Class ISO 3 as per ISO EN 14644-1;
3. Protection of the environment: This involves filtration of the expelled air quota with EN 1822 compliant HEPA H14 filters with an efficiency of 99.995% MPPS (equivalent to 99.999% on 0.3 mm particles with DOP/DOS test).
Made of AISI 304L stainless steel, with a lit worktop, fitted with a gas spring tilting front screen, it has a ventilation system consisting of 2 centrifugal fans, one of which is dedicated to the unidirectional air flow to the work area, accounting for 70 % of the air; the other dedicated to the amount of eject air, equal to 30 %
Basis configuration:- Blind worktop
- Floor support (integrated, third HEPA filter)
- Power socket
- Vacuum circuit with tap
- Gas circuit with tap and solenoid valve
- Front closure panel in anodised aluminium
- DES port 100 %
Optional accessories:- UV lamp (mounted on the front closure panel)
- Armrests (pair)
- Drawer chest on wheels, three drawers
- Additional activated carbon exhaust filter (without collar)
- Additional power socket
- Compressed air circuit with tap
- Nitrogen circuit with manual tap
- Dry contact NO/NC
CTH EVO
CLASS II
Extremely low energy consumption
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The CTH model is designed to meet three protection levels:
1. Protection of the operator: The containment index, evaluated over the total surface area of the frontal suction area, is equal to or less than 5 CFU for a nonturbulence test or APF equal to or greater than 1x105 according to EN12469;
2. Protection of the product: Cleanliness of the air in the working area in Class ISO 3 as per ISO EN 14644-1;
3. Protection of the environment: This involves filtration of the expelled air quota with EN 1822 compliant HEPA H14 filters with an efficiency of 99.995 % MPPS (equivalent to 99.999 % on 0.3 mm particles with DOP/DOS test).
The other dedicated to the amount of eject air, equal to 30%Made of AISI 304L stainless steel, with a lit worktop, fitted with an electrically operated, 7° inclined, shatterproof laminated glass front screen, it has a ventilation system consisting of 2 centrifugal fans, one of which is dedicated to the unidirectional air flow to the work area, accounting for 70 % of the air; the other dedicated to the amount of eject air, equal to 30 %
Basis configuration:
- Blind AISI 316L worktop single piece
- Floor support (integrated, third HEPA filter)
- 1 power socket for models 36 and 48
- 2 for models 60 and 72
- Vacuum circuit with tap
- Gas circuit with tap and solenoid valve
- DES port 100 %
Optional accessories:- UV lamp
- Armrests (pair)
- Drawer chest on wheels, three drawers
- Additional activated carbon exhaust filter (without collar)
- Additional power socket
- Dry contact NO/NC
CYTOBOX
CLASS III
Vacuum glove boxes with 2 material pass-throughs
CTH 36 - 48 - 72 Data sheet
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CYTOBOX is a negative pressure isolator with a unidirectional flow that isolates the operator and the environment from the process and its parts.
All the air is made to pass through a HEPA filter fitted under the work surface, to keep the working area clean and free from contaminants.
Fresh air is sucked from the top of the pass boxes through an H14 HEPA / ULPA filter and pushed into the working area of the pass boxes. Then air passing through a second HEPA / ULPA H14 filter is drawn in by the main fan.
The pressurised air pushed into the plenum passes through the HEPA / ULPA LAF H14 filter and then downwards, in a laminar flow, into the work chamber to protect the products being handled. From here, air is sucked into the main HEPA / ULPA H14 filter underneath the working surface, and then the air passes through the channel at the rear of the working chamber.
Part of the air is expelled through the exhaust HEPA H14 filter; this process creates a negative pressure condition in the working area to protect the operator and the environment.
CYTOBOX LIGHT
CLASS III
Glove boxes with material pass-throughs integrated into the worktop
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CYTOBOX LIGHT is a system mainly designed for the formulation of
antineoplastic drugs, i.e. used for the manipulation of pathogens, cytotoxic or
dangerous chemicals.
The filtration system consists of triple HEPA filtration level, at negative pressure, providing triple operator, environment and product protection. The polyethylene gloves, installed on the front screen, guarantee the ability of handling the agents/processing components, while at the same time ensuring physical separation between the handled products and the operators.
The body is made of cold rolled steel painted with antimicrobial coating. The internal surfaces and the worktop are made of stainless steel with smooth corners. The front screen of the main chamber is made with 8 mm thick anti-reflective safety glass, it can be fully opened for cleaning or maintenance purposes by means of two handles and a pair of gas springs.
The front and interior screens of the transfer hatch are made of PMMA, while the left and right side screens of the insulator body are made of 6 mm thick tempered glass. The transfer compartment hatches are interlocked and the exterior and interior doors are timed.
The gloves are made of neoprene material and separated by means of sleeves made of textile material with unmatched resistance.
VERTICAL LAMINAL FLOW HOODS
POLARIS
CLASS I
Positive pressure vertical laminar flow hood for product protection
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The POLARIS line is used in all situations where the product needs to be protected from harmful effects due to the uncontrolled spread of airborne contaminants during handling.
Since it is not a biological safety cabinet, it CANNOT be used to handle pathogens. It is used in quality control in the food industry, micromechanical assembly and nucleic acid amplification and thermocycling.
The POLARIS model is made of stainless steel, painted with epoxy powders, blind worktop in a single section and lit. The front glass is hinged to facilitate access even for large objects, fitted with gas springs to hold the opening position firm. The side walls are made of glass. Air filtration is entrusted to a H14 HEPA / ULPA filter with an efficiency greater than 99.995% MPPS (EN- 1822).
Basis configuration:
- AISI 304L stainless steel worktop with blind top in one indivisible sector
- Power socket (2 sockets for models 60 and 72)
- Side perforated windows
- DEHS port 100 %
Optional accessories:- Floor support
- Gas/vacuum/air/nitrogen/water taps
- Chest of drawers on wheels
- UV lamp to be placed on the front closing panel in stainless steel
- Additional power sockets
GEMINI
CLASS I
Compact Positive Pressure Vertical Laminar Flow Hood with Partial Recirculation
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The GEMINI line is used in all situations where the product needs to be protected from harmful effects due to the uncontrolled spread of airborne contaminants during handling.
Since it is not a biological safety cabinet, it CANNOT be used to handle pathogens.
It is used in quality control in the food industry, micromechanical assembly and nucleic acid amplification and thermocycling.
The GEMINI model is made of stainless steel, painted with epoxy powders, with the worktop perforated in a single section and lit. The front glass is hinged to facilitate access even for large objects, fitted with gas springs to hold the opening position firm.
The side walls are made of glass and have 2 holes for placing the service taps. Air filtration is entrusted to a H14 HEPA / ULPA filter with an efficiency greater than 99.995% MPPS (EN-1822).
Basis configuration:- DEHS port 100 %
- Electrical outlet
Optional accessories (supplied):- Support table in painted steel with/ without wheels
- Additional power sockets
- UV lamp with front closure panel
- Front closure panel WITHOUT UV lamp
- HEPA exhaust filter
- Air/nitrogen/vacuum taps
Horizontal Laminar Flow Hoods
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Helios hoods are classified with horizontal laminar flow and can be used in all situations where the product needs to be protected from harmful effects due to the uncontrolled spread of airborne contaminants during handling.
It ensures maximum worktop sterile conditions, therefore it is used for quality control in the food industry, micromechanical assemblies, preparation of nutritional parenteral therapies and in vitro fertilisation.
Since they are not biological safety cabinets, they CANNOT be used to handle pathogens.
The HELIOS model is made of steel, with safety tempered glass walls and equipped with fluorescent lamps positioned in an uncontaminated area. The ventilation system is provided by a fan dedicated to supplying the work area with a unidirectional flow of air; the fan is a double-intake centrifugal type with IP 55 protection rating.
Air filtration is carried out with a G3 pre-filter with high retention capacity and HEPA filter type ‘H14’ according to EN 1822 with 99.995 % MPPS efficiency.
Basis configuration:
- Power socket
- DEHS port 100 %
- No. 3 19 mm diameter through holes on each side glass for possible
- installation of taps
- Floor support
- Automatic air speed regulator with digital display
- Drawer chest on wheels, three drawers
- Gas/nitrogen/air/vacuum taps
- UV lamp, complete with curtain front screen
- Curtain front screen (WITHOUT UV lamp)
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